Oxytetracycline hydrochloride is a distinguished member of the tetracycline group of highly effective antibacterial drugs, known for its broad-spectrum activity.
This powerful antibiotic is meticulously produced by the renowned Streptomyces rimosus, a trusted source in the field of biotechnology.
Oxytetracycline hydrochloride, an antibiotic meticulously crafted by Streptomyces rimosus, boasts an impressive spectrum of antibacterial action. It is particularly effective against Streptococcusspp., including Staphylococcus spp. (even those strains that produce penicillinase),Listeria spp., known for causing severe infections,Bacillus anthracis, which causes anthrax, and Clostridiumspp., responsible for several serious conditions.Actinomyces israelii, Haemophilus influenzae, Haemophilus ducreyi, Bordetella pertussis, Escherichia coli, Enterobacter spp. (including Enterobacter aerogenes),Klebsiella spp., Salmonella spp., Shigella spp., Yersinia pestis, Bartonella bacilliformis, and Vibrio cholerae, which causes cholera, and Vibriofetus, Rickettsia spp., Borrelia burgdorferi, Brucella spp., Chromeria gherieeria, and Mycoplasma spp.
However, Oxytetracycline exhibits resistance against certain bacteria like:Pseudomonas aeruginosa, Proteus spp., Serratia spp., most strains of Bacteroides spp.,as well as fungiand viruses.
When administered intramuscularly, oxytetracycline hydrochloride is rapidly absorbed into the bloodstream, swiftly penetrating most body organs and tissues. The peak blood concentration is achieved within 30 minutes, maintaining a therapeutic level for 10-12 hours.and tissues is sustained for 10-12 hours.
Oxytetracycline is primarily excreted from the body through urine, ensuring efficient elimination.
Indications for use include:
Oxytetracycline hydrochloride for injection is specifically utilized in farm animals to treat respiratory bacterial infections, colibacteriosis, salmonellosis, pasteurellosis,bacterial gastroenterocolitis in young animals, mastitis, gynecological ailments, and other diseases caused by pathogens susceptible to tetracycline antibiotics.
Before use, the drug in thevial, punctured with a sterile needle, should be dissolvedin 5-10mlof sterile waterforinjection,or a sterile isotonic solution of sodium chloride, or a 1-2% sterile solution of novocaine.
The treatment solution must be prepared immediately before administration and is not suitable for storage or heating.
Administration route
The drug is administered to animals intramuscularly at intervals of 10-12 hours for 5-7 days in the following doses
(according to the active substance):
Calves up to 6 months of ageand lambsuptoFor animals up to 4 months of age, administer 9mg/kg ofanimalweight.For piglets up to 6 months of age, administer 12mg/kg ofanimal weight.
For cattle and pigs older than 6 months of age, and small cattleolder than 4 months of age, administer 7mg/kg of animalweight.
Withdrawal period:
Slaughter of animals for meat is allowed no earlierthan 6 days after the last use of the drug.
Storage:
Keep tightly sealed, and store in a dry place.